Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LSS | P48449 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.48 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | VHL | P40337 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12133623 | 0.85 | KMT2A (0.76) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL23754981 | 0.85 | LSS (0.56) | KMT2ALSSHDAC6ALDH1A1HRH3 | |
| SCHEMBL12522662 | 0.85 | KMT2A (0.46) | KMT2ALSSHDAC1HDAC6MAPT | |
| SCHEMBL9242992 | 0.81 | ALDH1A1 (0.61) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL11436461 | 0.79 | TGM2 (0.63) | KMT2ALSSHDAC6ALDH1A1HRH3 | |
| SCHEMBL20830601 | 0.79 | KMT2A (0.41) | KMT2ALSSHDAC1HDAC6MAPT | |
| SCHEMBL19682898 | 0.78 | KMT2A (0.66) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL3612554 | 0.78 | KMT2A (0.66) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL1951513 | 0.78 | KMT2A (0.66) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL3612557 | 0.78 | KMT2A (0.66) | KMT2AHDAC1HDAC6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |