Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 17/20 | 0.47 |
| ▸ | NPY1R | P25929 | 11/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.47 |
| ▸ | NPY2R | P49146 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20739105 | 0.92 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7607468 | 0.92 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL84332 | 0.92 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL20158427 | 0.92 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL15692085 | 0.92 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL12944390 | 0.92 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL22315797 | 0.92 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL28466191 | 0.91 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL28466185 | 0.91 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16770343 | 0.89 | SIRT1 (0.39) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632210-B2 | Peptidomimetic compounds and antibody-drug conjugates thereof | GENENTECH, INC. (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190083643-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10632210-B2 | Peptidomimetic compounds and antibody-drug conjugates thereof | DNPEP, LNPEP, BCR | NPY4R 1417/4885NPY1R 1724/4885NPY5R 1926/4885 |
| US-20190083643-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | DNPEP, LNPEP, BCR | NPY4R 1417/4885NPY1R 1724/4885NPY5R 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.