SCHEMBL20831733

SCHEMBL20831733

CN1C(=O)c2ccc3c4c(ccc(c24)C1=O)CC=C3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.37
KMT2A Q03164 6/20 0.37
ALDH1A1 P00352 6/20 0.37
HPGD P15428 4/20 0.37
KDM4E B2RXH2 3/20 0.37
USP2 O75604 2/20 0.37
KEAP1 Q14145 2/20 0.37
NFE2L2 Q16236 2/20 0.37
ATM Q13315 1/20 0.37
POLB P06746 3/20 0.36
PRMT1 Q99873 1/20 0.36
L3MBTL1 Q9Y468 4/20 0.35
MAPT P10636 3/20 0.35
HSD17B10 Q99714 3/20 0.35
ALOX15 P16050 2/20 0.35
TERT O14746 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23551965 0.83 KDM4E (0.31) ALDH1A1HPGDKDM4EPOLBTDP1
SCHEMBL5384450 0.80 PARP1 (0.37) MEN1KMT2AUSP2POLBMAPT
SCHEMBL18904599 0.79 MEN1 (0.46) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL20832212 0.77 TYMS (0.37) ALOX15TDP1TUBB4ATUBBTUBA3C
SCHEMBL4361402 0.76 CA1 (0.32)
SCHEMBL30937815 0.74 MEN1 (0.55) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL127059 0.74 MEN1 (0.55) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL4854636 0.74 CA1 (0.33) ALDH1A1KEAP1NFE2L2ATML3MBTL1
SCHEMBL17032011 0.73 ALDH1A1 (0.54) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL21375363 0.73 ALDH1A1 (0.40) MEN1KMT2AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US disclosed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US disclosed
US-10875946-B2 Polyolefin dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2020-12-29 US disclosed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US disclosed
WO-2019055978-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF CHEVRON ORONITE COMPANY LLC (US) 2019-03-21 WO disclosed