Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361402 | 0.83 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL20832212 | 0.80 | TYMS (0.37) | — | |
| SCHEMBL4856747 | 0.79 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL5384450 | 0.77 | PARP1 (0.37) | — | |
| SCHEMBL20531212 | 0.76 | ALDH1A1 (0.45) | CA1CA2ALDH1A1TSHRMAPK1 | |
| Hydrogen Sulfide SCHEMBL9423498 | 0.74 | ALDH1A1 (0.43) | CA1CA2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20831733 | 0.74 | MEN1 (0.37) | ALDH1A1MAPK1ATMHSD17B10L3MBTL1 | |
| SCHEMBL23551965 | 0.71 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL7637856 | 0.69 | CA1 (0.43) | CA1CA2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL20010382 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013076646-A1 | A NEW DIAZA-BENZOFLUORANTHENE DERIVATIVE AS DRUG | RICHTER GEDEON NYRT. (HU) | 2013-05-30 | — | — | WO | disclosed |
| US-7470290-B2 | Hydroscopic polymer gels for easier cleaning | THE CLOROX COMPANY (US) | 2008-12-30 | — | — | US | disclosed |
| US-7183010-B2 | Organic light-emitting diode devices with improved operational stability | EASTMAN KODAK CORPORATION (US) | 2007-02-27 | — | — | US | disclosed |
| US-20050245428-A1 | Hydroscopic polymer gels for easier cleaning | RODRIGUES KLIN A | 2005-11-03 | — | — | US | disclosed |
| US-20040076853-A1 | Organic light-emitting diode devices with improved operational stability | EASTMAN KODAK COMPANY | 2004-04-22 | — | — | US | disclosed |