Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 6/20 | 0.39 |
| ▸ | TNKS | O95271 | 4/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818726 | 0.87 | TRPC5 (0.57) | TRPC5ALDH1A1PARP1TNKSTNKS2 | |
| SCHEMBL20831978 | 0.81 | TRPC5 (0.59) | TRPC5ALDH1A1 | |
| SCHEMBL20831509 | 0.78 | TRPC5 (0.54) | TRPC5ALDH1A1PARP1TNKSTNKS2 | |
| SCHEMBL20831513 | 0.77 | TRPC5 (0.60) | TRPC5ALDH1A1PARP1TNKSTNKS2 | |
| SCHEMBL20817854 | 0.76 | TRPC5 (0.71) | TRPC5ALDH1A1 | |
| SCHEMBL20831703 | 0.76 | TRPC5 (0.68) | TRPC5ALDH1A1PARP1TNKSTNKS2 | |
| SCHEMBL20818532 | 0.76 | TRPC5 (0.74) | TRPC5ALDH1A1 | |
| SCHEMBL25699638 | 0.76 | TRPC5 (0.56) | TRPC5ALDH1A1PARP1TNKSTNKS2 | |
| SCHEMBL20818246 | 0.74 | TRPC5 (0.54) | TRPC5ALDH1A1PARP1TNKSTNKS2 | |
| SCHEMBL20831298 | 0.74 | TRPC5 (0.53) | TRPC5ALDH1A1PARP1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |