Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20817854 | 0.83 | TRPC5 (0.71) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20831762 | 0.81 | TRPC5 (0.48) | TRPC5ALDH1A1 | |
| SCHEMBL20818532 | 0.81 | TRPC5 (0.74) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20817888 | 0.81 | TRPC5 (0.67) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20817903 | 0.79 | TRPC5 (0.70) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20818536 | 0.79 | TRPC5 (0.70) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20818543 | 0.78 | TRPC5 (0.63) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20831681 | 0.77 | TRPC5 (0.77) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20818388 | 0.75 | TRPC5 (0.67) | TRPC5ALDH1A1POLBTIPARPKCNH2 | |
| SCHEMBL20831680 | 0.75 | TRPC5 (0.61) | TRPC5ALDH1A1POLBTIPARPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |