Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25704592 | 0.85 | CA12 (0.40) | TRPC5CA12CA1CA2CA9 | |
| SCHEMBL20831517 | 0.81 | TRPC5 (0.56) | TRPC5 | |
| SCHEMBL20831994 | 0.80 | TRPC5 (0.33) | TRPC5CA12CA1CA2CA9 | |
| SCHEMBL20831527 | 0.67 | TRPC5 (0.54) | TRPC5 | |
| SCHEMBL20831676 | 0.67 | TRPC5 (0.36) | TRPC5 | |
| SCHEMBL20831522 | 0.66 | TRPC5 (0.56) | TRPC5 | |
| SCHEMBL20831523 | 0.64 | TIPARP (0.55) | TRPC5 | |
| SCHEMBL20831537 | 0.64 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL20831314 | 0.62 | TIPARP (0.58) | TRPC5 | |
| SCHEMBL20831621 | 0.62 | RAB9A (0.33) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |