Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 11/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831221 | 0.77 | TRPC5 (1.00) | TRPC5POLBALDH1A1 | |
| SCHEMBL20818507 | 0.75 | TRPC5 (0.61) | TRPC5POLBTIPARPALDH1A1 | |
| SCHEMBL20831227 | 0.72 | POLB (0.68) | TRPC5POLBTIPARPALDH1A1 | |
| SCHEMBL25694464 | 0.72 | TRPC5 (0.60) | TRPC5POLBTIPARPALDH1A1 | |
| SCHEMBL20818445 | 0.72 | TRPC5 (0.61) | TRPC5POLBTIPARPALDH1A1 | |
| SCHEMBL20831216 | 0.71 | TRPC5 (0.60) | TRPC5POLBTIPARPALDH1A1 | |
| SCHEMBL20817850 | 0.70 | TRPC5 (0.58) | TRPC5POLBTIPARPALDH1A1 | |
| SCHEMBL25694641 | 0.70 | TRPC5 (1.00) | TRPC5POLBALDH1A1 | |
| SCHEMBL20817984 | 0.69 | TRPC5 (0.91) | TRPC5POLBALDH1A1 | |
| SCHEMBL25275764 | 0.69 | TRPC5 (0.60) | TRPC5POLBTIPARPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |