Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20817984 | 0.95 | TRPC5 (0.91) | TRPC5ALDH1A1HSP90AA1HSP90AB1CA12 | |
| SCHEMBL4813164 | 0.85 | ALDH1A1 (1.00) | TRPC5ALDH1A1HSP90AA1HSP90AB1DRD2 | |
| SCHEMBL20818595 | 0.85 | TRPC5 (0.74) | TRPC5ALDH1A1HSP90AA1HSP90AB1DRD2 | |
| SCHEMBL20818113 | 0.83 | TRPC5 (1.00) | TRPC5ALDH1A1 | |
| SCHEMBL20831213 | 0.81 | TRPC5 (0.77) | TRPC5ALDH1A1POLB | |
| SCHEMBL20818230 | 0.79 | TRPC5 (0.65) | TRPC5ALDH1A1HSP90AA1HSP90AB1TDP1 | |
| SCHEMBL30476388 | 0.79 | TRPC5 (1.00) | TRPC5ALDH1A1 | |
| SCHEMBL20818084 | 0.79 | TRPC5 (1.00) | TRPC5ALDH1A1 | |
| SCHEMBL20831223 | 0.77 | TRPC5 (0.77) | TRPC5ALDH1A1 | |
| SCHEMBL4814200 | 0.77 | ALDH1A1 (0.68) | TRPC5ALDH1A1HSP90AA1HSP90AB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | PDXK, ATP6V1B1, REN | TRPC5 1439/4885ALDH1A1 649/4885HSP90AA1 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.