Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730153 | 0.78 | MAPK8 (0.32) | LMNA | |
| SCHEMBL21420046 | 0.76 | POLB (0.40) | TSHR | |
| SCHEMBL14487702 | 0.76 | POLB (0.40) | TSHR | |
| SCHEMBL18854115 | 0.71 | — | — | |
| SCHEMBL14555879 | 0.64 | LMNA (0.47) | LMNATSHRNPSR1 | |
| SCHEMBL14487939 | 0.64 | LMNA (0.47) | LMNATSHRNPSR1 | |
| SCHEMBL15723842 | 0.62 | — | — | |
| SCHEMBL24194158 | 0.62 | — | — | |
| SCHEMBL12124398 | 0.61 | KDM4E (0.38) | PDE2ALMNA | |
| SCHEMBL14487851 | 0.60 | LMNA (0.52) | LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190084963-A1 | Solid Forms Of an HIV Capsid Inhibitor | GILEAD SCIENCES, INC. | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084963-A1 | Solid Forms Of an HIV Capsid Inhibitor | ZC3HAV1, ZC3HAV1L, PRNP | PDE2A 3782/4885PDE4A 3794/4885PDE4B 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.