Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833581 | 0.90 | MRGPRX4 (0.49) | MRGPRX4LRRK2 | |
| SCHEMBL22066298 | 0.90 | TACR1 (0.42) | TACR1BTN3A1MRGPRX4LRRK2KCNQ3 | |
| SCHEMBL18973553 | 0.89 | BTN3A1 (0.48) | TACR1BTN3A1MRGPRX4PPARGPPARD | |
| SCHEMBL20833582 | 0.85 | BTN3A1 (0.43) | BTN3A1MRGPRX4PPARGHTT | |
| SCHEMBL22065046 | 0.85 | BTN3A1 (0.39) | BTN3A1MRGPRX4HTT | |
| SCHEMBL22066299 | 0.83 | BTN3A1 (0.39) | TACR1BTN3A1MRGPRX4HTT | |
| SCHEMBL22066301 | 0.83 | MRGPRX4 (0.43) | TACR1BTN3A1MRGPRX4LRRK2HTT | |
| SCHEMBL22065039 | 0.82 | BTN3A1 (0.51) | BTN3A1MRGPRX4 | |
| SCHEMBL24793362 | 0.82 | BTN3A1 (0.41) | BTN3A1MRGPRX4MGLLHTT | |
| SCHEMBL24793363 | 0.82 | BTN3A1 (0.43) | BTN3A1MRGPRX4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053476-A1 | FLOXURIDINE SYNTHESIS | NuCana plc (GB) | 2019-03-21 | — | — | WO | disclosed |