Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22066300 | 0.90 | BTN3A1 (0.39) | BTN3A1HTTMRGPRX4PPARGSLC6A4 | |
| SCHEMBL22066301 | 0.90 | MRGPRX4 (0.43) | BTN3A1HTTMRGPRX4MAPTALDH1A1 | |
| SCHEMBL22065046 | 0.90 | BTN3A1 (0.39) | BTN3A1HTTMRGPRX4SLC6A4ELANE | |
| SCHEMBL22066302 | 0.90 | BTN3A1 (0.39) | BTN3A1HTTMRGPRX4SLC6A4ELANE | |
| SCHEMBL22066299 | 0.90 | BTN3A1 (0.39) | BTN3A1HTTMRGPRX4ELANECASP1 | |
| SCHEMBL18973552 | 0.89 | BTN3A1 (0.52) | BTN3A1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL22065039 | 0.88 | BTN3A1 (0.51) | BTN3A1MRGPRX4ELANECASP1MAPT | |
| SCHEMBL22066276 | 0.87 | MEN1 (0.39) | BTN3A1HTTSLC6A4CASP1MAPT | |
| SCHEMBL24793363 | 0.87 | BTN3A1 (0.43) | BTN3A1HTTMRGPRX4ELANECASP1 | |
| SCHEMBL15203143 | 0.86 | BTN3A1 (0.42) | BTN3A1MRGPRX4ELANECASP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2022-12-22 | — | — | US | disclosed |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
| WO-2019053476-A1 | FLOXURIDINE SYNTHESIS | NuCana plc (GB) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PPA1, PPIP5K2, TYMP | BTN3A1 4531/4885HTT 3894/4885MRGPRX4 4643/4885 |
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PNP, NTPCR, TYMP | BTN3A1 2948/4885HTT 4051/4885MRGPRX4 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.