Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833582 | 0.90 | BTN3A1 (0.43) | MRGPRX4BTN3A1ALDH1A1HTTMAPT | |
| SCHEMBL22066299 | 0.90 | BTN3A1 (0.39) | MRGPRX4BTN3A1ALDH1A1HPGDHTT | |
| SCHEMBL22065040 | 0.89 | BTN3A1 (0.48) | MRGPRX4BTN3A1ALDH1A1HPGDLRRK2 | |
| SCHEMBL22065045 | 0.89 | POLB (0.42) | MRGPRX4BTN3A1POLBG6PDALDH1A1 | |
| SCHEMBL22066302 | 0.88 | BTN3A1 (0.39) | MRGPRX4BTN3A1POLBG6PDALDH1A1 | |
| SCHEMBL22065646 | 0.87 | POLB (0.41) | MRGPRX4BTN3A1POLBG6PDALDH1A1 | |
| SCHEMBL20833581 | 0.86 | MRGPRX4 (0.49) | MRGPRX4LRRK2 | |
| SCHEMBL22065043 | 0.85 | BTN3A1 (0.47) | BTN3A1POLBG6PDALDH1A1HPGD | |
| SCHEMBL22066004 | 0.85 | POLB (0.39) | MRGPRX4BTN3A1POLBG6PDALDH1A1 | |
| SCHEMBL22065044 | 0.84 | BTN3A1 (0.43) | MRGPRX4BTN3A1POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2022-12-22 | — | — | US | disclosed |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PPA1, PPIP5K2, TYMP | MRGPRX4 4643/4885BTN3A1 4531/4885POLB 450/4885 |
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PNP, NTPCR, TYMP | MRGPRX4 4449/4885BTN3A1 2948/4885POLB 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.