Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833677 | 1.00 | ADRB2 (0.55) | ADRB2MAPTALDH1A1CA12CA2 | |
| SCHEMBL20833680 | 1.00 | ADRB2 (0.55) | ADRB2MAPTALDH1A1CA12CA2 | |
| SCHEMBL20819511 | 0.87 | ADRB2 (0.72) | ADRB2ALDH1A1ADRB1ADRB3KDM4E | |
| SCHEMBL20819512 | 0.87 | ADRB2 (0.72) | ADRB2ALDH1A1ADRB1ADRB3KDM4E | |
| SCHEMBL20836632 | 0.87 | ADRB2 (0.72) | ADRB2ALDH1A1ADRB1ADRB3KDM4E | |
| SCHEMBL19330048 | 0.87 | ADRB2 (0.72) | ADRB2ALDH1A1ADRB1ADRB3KDM4E | |
| SCHEMBL20836555 | 0.85 | ADRB2 (0.54) | ADRB2MAPTALDH1A1ADRB1ADRB3 | |
| SCHEMBL22362377 | 0.85 | ADRB2 (0.54) | ADRB2MAPTALDH1A1ADRB1ADRB3 | |
| SCHEMBL22362370 | 0.85 | ADRB2 (0.54) | ADRB2MAPTALDH1A1ADRB1ADRB3 | |
| SCHEMBL20819621 | 0.85 | ADRB2 (0.54) | ADRB2MAPTALDH1A1ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053426-A1 | FLUOROPHENYL BETA-HYDROXYETHYLAMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2019-03-21 | — | — | WO | disclosed |