Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819512 | 1.00 | ADRB2 (0.72) | ADRB2HIF1AALDH1A1HTR1ATHPO | |
| SCHEMBL20819511 | 1.00 | ADRB2 (0.72) | ADRB2HIF1AALDH1A1HTR1ATHPO | |
| SCHEMBL19330048 | 1.00 | ADRB2 (0.72) | ADRB2HIF1AALDH1A1HTR1ATHPO | |
| Acetic Acid SCHEMBL20819508 | 0.93 | ADRB2 (0.63) | ADRB2HIF1AALDH1A1HTR1ATHPO | |
| Acetic Acid SCHEMBL19329777 | 0.93 | ADRB2 (0.63) | ADRB2HIF1AALDH1A1HTR1ATHPO | |
| Acetic Acid SCHEMBL20819510 | 0.93 | ADRB2 (0.63) | ADRB2HIF1AALDH1A1HTR1ATHPO | |
| SCHEMBL20833680 | 0.87 | ADRB2 (0.55) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL20833677 | 0.87 | ADRB2 (0.55) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL20833683 | 0.87 | ADRB2 (0.55) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL19329750 | 0.86 | ADRB2 (0.67) | ADRB2HIF1AALDH1A1HTR1ATHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793774-B2 | Chiral beta-hydroxyethylamines and their use in the treatment of hyperglycemia | ATROGI AB (SE) | 2023-10-24 | — | — | US | disclosed |
| US-11793774-B2 | Chiral beta-hydroxyethylamines and their use in the treatment of hyperglycemia | ATROGI AB (SE) | 2023-10-24 | — | — | US | disclosed |
| US-20200268687-A1 | CHIRAL BETA-HYDROXYETHYLAMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCEMIA | ATROGI AB (SE) | 2020-08-27 | — | — | US | disclosed |
| US-20200268687-A1 | CHIRAL BETA-HYDROXYETHYLAMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCEMIA | ATROGI AB (SE) | 2020-08-27 | — | — | US | disclosed |
| WO-2019053429-A1 | CHIRAL BETA-HYDROXYETHYLAMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCEMIA | ATROGI AB (SE) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11793774-B2 | Chiral beta-hydroxyethylamines and their use in the treatment of hyperglycemia | GPR119, SLC5A1, SLC5A2 | ADRB2 54/4885HIF1A 445/4885ALDH1A1 832/4885 |
| US-20200268687-A1 | CHIRAL BETA-HYDROXYETHYLAMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCEMIA | GPR119, SLC5A1, SLC5A2 | ADRB2 54/4885HIF1A 445/4885ALDH1A1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.