Sugi Predict

Sugi Predict / Compounds / SCHEMBL208348

SCHEMBL208348

SCHEMBL208348

CCOC(=O)C1(NC=O)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGAM O43451 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ SI P14410 1/20 0.37
▸ MGAM2 Q2M2H8 1/20 0.37
▸ POLB P06746 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ OPRM1 P35372 6/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ OPRD1 P41143 3/20 0.33
▸ OPRK1 P41145 3/20 0.33
▸ SLC22A1 O15245 1/20 0.33
▸ SLC6A4 P31645 1/20 0.33
▸ ADRA1A P35348 1/20 0.33
▸ KCNH2 Q12809 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27800263 0.82 ALDH1A1 (0.38) MGAMGAASIMGAM2POLB
SCHEMBL9033449 0.79 NPSR1 (0.38) ALDH1A1NPSR1LMNA
SCHEMBL2787784 0.78 MGAM (0.41) MGAMGAASIMGAM2POLB
Hydrochloric Acid SCHEMBL2787783 0.76 MGAM (0.39) MGAMGAASIMGAM2POLB
SCHEMBL19442305 0.76 MGAM (0.39) MGAMGAASIMGAM2POLB
SCHEMBL1508731 0.76 MGAM (0.44) MGAMGAASIMGAM2POLB
SCHEMBL9886521 0.76 MGAM (0.39) MGAMGAASIMGAM2POLB
SCHEMBL9782049 0.74 ALDH1A1 (0.41) MGAMGAASIMGAM2POLB
SCHEMBL22822489 0.74 ALOX15 (0.43) MGAMGAASIMGAM2POLB
SCHEMBL12323493 0.74 ALDH1A1 (0.35) MGAMGAASIMGAM2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4554017-A Method and compositions for regulating plant growth using cycloalkane-carboxylic acid compounds BAYER AKTIENGESELLSCHAFT (DE) 1985-11-19 — — US claimed
EP-1270557-B1 ETHYLENEDIAMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2012-07-25 — — EP disclosed
EP-2431370-A1 Monoacylated 1,2-diaminocycloalkanes DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2012-03-21 — — EP disclosed
US-8088796-B2 Triamine derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-01-03 — — US disclosed
US-20110312990-A1 Diamine Derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-12-22 — — US disclosed
US-8058440-B2 Process for producing 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-11-15 — — US disclosed
EP-2343290-A1 Diamine derivatives as factor X inhibitors Daiichi Sankyo Company, Limited (JP) 2011-07-13 — — EP disclosed
US-7935824-B2 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2011-05-03 — — US disclosed
US-20110077266-A1 Diamine Derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-03-31 — — US disclosed
US-20110054177-A1 PROCESS FOR PRODUCING 5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-c]PYRIDINE-2-CARBOXYLIC ACID DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2011-03-03 — — US disclosed
US-20050245565-A1 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-11-03 — — US disclosed
EP-1577302-A1 NOVEL ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 — — EP disclosed
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 — — EP disclosed
US-20050119486-A1 Diamine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2005-06-02 — — US disclosed
US-20050020645-A1 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-01-27 — — US disclosed
US-20040122063-A1 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-24 — — US disclosed
EP-1415992-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-05-06 — — EP disclosed
EP-1405852-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-07 — — EP disclosed
EP-1270557-A1 ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-01-02 — — EP disclosed
EP-0705835-A1 Quinoxalic-2,3-diones with an oxa or thiaheterocyclic fused ring CIBA-GEIGY AG (CH) 1996-04-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054177-A1 PROCESS FOR PRODUCING 5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-c]PYRIDINE-2-CARBOXYLIC ACID PAH, CA4, TET2 MGAM 879/4885GAA 843/4885SI 596/4885
US-20050020645-A1 Diamine derivatives C9, C1S, C1R MGAM 4056/4885GAA 4788/4885SI 2573/4885
US-20050245565-A1 Diamine derivatives C9, C1S, C1R MGAM 4056/4885GAA 4788/4885SI 2573/4885
US-20050119486-A1 Diamine derivatives C9, C1S, C1R MGAM 4056/4885GAA 4788/4885SI 2573/4885
US-20110077266-A1 Diamine Derivatives F2, TFPI, F3 MGAM 1770/4885GAA 2113/4885SI 3137/4885
US-20110312990-A1 Diamine Derivatives C9, C1S, C1R MGAM 4130/4885GAA 4829/4885SI 2610/4885
US-20040122063-A1 Ethylenediamine derivatives ECE1, F2, ECE2 MGAM 4829/4885GAA 4278/4885SI 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.