Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Alanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.59 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.59 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.59 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL14677168 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| D-Alanine SCHEMBL1537294 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL186137 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL6534719 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL17513685 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL1675385 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL25189736 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL819876 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL8383645 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL157005 | 1.00 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218729-A1 | RECOMBINANT PROTEIN FOR NEUTERING OR SPAYING ANIMAL, AND VACCINE COMPOSITION COMPRISING SAME | BIOAPPLICATIONS INC. (KR) | 2023-07-13 | — | — | US | claimed |
| US-20230173044-A1 | RECOMBINANT PROTEIN FOR REMOVING BOAR TAINT AND VACCINE COMPOSITION COMPRISING THE SAME | BIOAPPLICATIONS INC. (KR) | 2023-06-08 | — | — | US | claimed |
| WO-2023040793-A1 | ANTI-INFLAMMATORY COMPOUND AND USE THEREOF | 映恩生物制药（苏州）有限公司 | 2023-03-23 | — | — | WO | claimed |
| EP-4129326-A1 | RECOMBINANT PROTEIN FOR NEUTERING OR SPAYING ANIMAL, AND VACCINE COMPOSITION COMPRISING SAME | Bioapplications Inc. (KR) | 2023-02-08 | — | — | EP | claimed |
| CN-115066256-A | Recombinant protein for animal sterilization or castration and vaccine composition comprising the same | 巴伊沃爱普有限公司 | 2022-09-16 | — | — | CN | claimed |
| EP-3925617-A1 | RECOMBINANT PROTEIN FOR ELIMINATING BOAR TAINT AND VACCINE COMPOSITION COMPRISING SAME | Bioapplications Inc. (KR) | 2021-12-22 | — | — | EP | claimed |
| CN-113747916-A | Recombinant protein for eliminating male odor and vaccine composition containing same | 巴伊沃爱普有限公司 | 2021-12-03 | — | — | CN | claimed |
| EP-1498476-B1 | MUTATED ALKALINE CELLULASE | KAO CORP (JP) | 2008-10-15 | — | — | EP | claimed |
| US-7364891-B2 | Mutated alkaline cellulase | KAO CORPORATION (JP) | 2008-04-29 | — | — | US | claimed |
| US-20050287656-A1 | Mutated alkaline cellulase | KAO CORPORATION (JP) | 2005-12-29 | — | — | US | claimed |
| EP-1498476-A1 | MUTATED ALKALINE CELLULASE | Kao Corporation (JP) | 2005-01-19 | — | — | EP | claimed |
| EP-4213941-A1 | MULTIEPITOPE VACCINE FOR THE TREATMENT OF ALZHEIMER'S DISEASE | OTHAIR PROTHENA LIMITED (IE) | 2023-07-26 | — | — | EP | disclosed |
| US-20230218729-A1 | RECOMBINANT PROTEIN FOR NEUTERING OR SPAYING ANIMAL, AND VACCINE COMPOSITION COMPRISING SAME | BIOAPPLICATIONS INC. (KR) | 2023-07-13 | — | — | US | disclosed |
| US-20230173044-A1 | RECOMBINANT PROTEIN FOR REMOVING BOAR TAINT AND VACCINE COMPOSITION COMPRISING THE SAME | BIOAPPLICATIONS INC. (KR) | 2023-06-08 | — | — | US | disclosed |
| CN-115851604-A | HPV16/18 tumor cell line and establishment and application of cell line animal model | 北京循生生物医学研究有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-1498476-A1 | MUTATED ALKALINE CELLULASE | Kao Corporation (JP) | 2005-01-19 | — | — | EP | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-20040063754-A1 | Dehalogeno compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1336611-A1 | DEHALOGENO COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-4340592-A | OLICOPEPTIDES FOR DIETARY PURPOSES | ADIBI SIAMAK A | 1982-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063754-A1 | Dehalogeno compounds | DEK, PGLS, RPS27L | GLRA1 1962/4885SLC6A9 1053/4885OR51E2 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.