Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678345 | 0.91 | EPHX1 (0.39) | HSD11B1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL16667915 | 0.91 | EPHX1 (0.39) | HSD11B1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL16667917 | 0.91 | EPHX1 (0.39) | HSD11B1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL13747445 | 0.86 | MEN1 (0.46) | HSD11B1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL31679498 | 0.84 | HSD11B1 (0.56) | HSD11B1CYP2C9CTSKCA1CA2 | |
| SCHEMBL8266320 | 0.83 | USP30 (0.40) | HSD11B1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL208443 | 0.82 | HSD11B1 (0.46) | HSD11B1CYP2C9PDE4BCTSKCA1 | |
| SCHEMBL206613 | 0.81 | PDE4B (0.48) | HSD11B1MEN1KMT2APDE4BCTSK | |
| SCHEMBL29385582 | 0.81 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL16164661 | 0.79 | PDE4B (0.56) | HSD11B1CYP2C9KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088796-B2 | Triamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20090239857-A1 | TRIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239857-A1 | TRIAMINE DERIVATIVE | F2, F12, F3 | HSD11B1 1245/4885CYP2C9 199/4885MEN1 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.