Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208443 | 0.88 | HSD11B1 (0.46) | HSD11B1CYP2C9CTSKCA1CA2 | |
| SCHEMBL208362 | 0.86 | HSD11B1 (0.40) | MEN1KMT2AALDH1A1TSHRHSD11B1 | |
| SCHEMBL14911483 | 0.84 | PDE4B (0.56) | KMT2AHSD11B1CYP2C9L3MBTL1PDE4B | |
| SCHEMBL16164661 | 0.84 | PDE4B (0.56) | KMT2AHSD11B1CYP2C9L3MBTL1PDE4B | |
| SCHEMBL15081499 | 0.84 | CTSK (0.43) | MEN1KMT2AALDH1A1TSHRHSD11B1 | |
| SCHEMBL16170288 | 0.84 | CTSK (0.43) | MEN1KMT2AALDH1A1TSHRHSD11B1 | |
| SCHEMBL14908812 | 0.84 | CTSK (0.43) | MEN1KMT2AALDH1A1TSHRHSD11B1 | |
| SCHEMBL207555 | 0.84 | CTSK (0.43) | MEN1KMT2AALDH1A1TSHRHSD11B1 | |
| SCHEMBL32684148 | 0.84 | MEN1 (0.47) | MEN1KMT2AALDH1A1TSHRHSD11B1 | |
| SCHEMBL30738868 | 0.83 | MEN1 (0.50) | MEN1KMT2AALDH1A1TSHRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576135-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576135-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |