SCHEMBL20836740

SCHEMBL20836740

Cc1ccc(S(=O)(=O)OCCc2ccc(CNC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.46
CA1 P00915 6/20 0.46
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
LMNA P02545 3/20 0.38
ALDH1A1 P00352 4/20 0.37
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
NR1H4 Q96RI1 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20836747 0.88 CA2 (0.51) CA2CA1KMT2ALMNAALDH1A1
SCHEMBL21101050 0.87 CA1 (0.43) CA2CA1MEN1KMT2ASMN1; SMN2
SCHEMBL10177832 0.85 CA1 (0.47) CA2CA1MEN1KMT2ALMNA
SCHEMBL12187832 0.83 CA1 (0.42) CA2CA1MEN1KMT2ALMNA
SCHEMBL12187846 0.83 CA1 (0.42) CA2CA1MEN1KMT2ALMNA
SCHEMBL15010853 0.83 CA1 (0.42) CA2CA1MEN1KMT2ALMNA
SCHEMBL15684582 0.81 CA2 (0.49) CA2CA1KMT2ASMN1; SMN2MAPT
SCHEMBL27446329 0.81 CA1 (0.42) CA2CA1MEN1KMT2ALMNA
SCHEMBL19361359 0.79 CA1 (0.46) CA2CA1NR1H4MAPT
SCHEMBL16216340 0.79 CA1 (0.46) CA2CA1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 US disclosed
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. 2022-10-27 US disclosed
EP-3567029-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS Lantheus Medical Imaging, Inc. (US) 2019-11-13 EP disclosed
EP-2753605-B1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING INC (US) 2019-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 CA2 992/4885CA1 85/4885MEN1 80/4885
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 CA2 992/4885CA1 85/4885MEN1 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.