Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | WEE1 | P30291 | 5/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | MST1R | Q04912 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398034 | 0.84 | ABCG2 (0.58) | KDM1AADRA2AADRA2BADRA2CJAK2 | |
| SCHEMBL374708 | 0.82 | HCK (0.58) | KDM1AADRA2AADRA2BADRA2CWEE1 | |
| SCHEMBL20816283 | 0.81 | MAPT (0.54) | KDM1AADRA2AADRA2BADRA2CWEE1 | |
| SCHEMBL2377742 | 0.75 | RAD52 (0.62) | KDM1AADRA2AADRA2BADRA2CRAD52 | |
| SCHEMBL14660127 | 0.74 | CD274 (0.57) | KDM1AADRA2AADRA2BADRA2CWEE1 | |
| SCHEMBL374566 | 0.72 | CDK9 (0.53) | KDM1AADRA2AADRA2BADRA2CWEE1 | |
| SCHEMBL373634 | 0.72 | HCK (0.56) | KDM1AADRA2AADRA2BADRA2CWEE1 | |
| SCHEMBL19848775 | 0.71 | HCK (0.55) | KDM1AADRA2AADRA2BADRA2CWEE1 | |
| SCHEMBL4724629 | 0.71 | GAA (0.50) | KDM1AADRA2AADRA2BADRA2CFGFR1 | |
| SCHEMBL4941458 | 0.71 | FGFR4 (0.43) | WEE1ALKFGFR1PDGFRACDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190083499-A1 | CHLOROBENZENE SUBSTITUTED AZAARYL COMPOUNDS | TAIPEI MEDICAL UNIVERSITY (TW) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190083499-A1 | CHLOROBENZENE SUBSTITUTED AZAARYL COMPOUNDS | MKI67, CTCF, CDKN1A | KDM1A 209/4885ADRA2A 2743/4885ADRA2B 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.