Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 2/20 | 0.53 |
| ▸ | CCNK | O75909 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CCND3 | P30281 | 1/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374566 | 0.84 | CDK9 (0.53) | CDK9CCNKCCNA2CDK2CCND3 | |
| SCHEMBL20837413 | 0.81 | KDM1A (0.51) | MAPTMEN1MAPK1KMT2ATDP1 | |
| SCHEMBL14081268 | 0.78 | LMNA (0.82) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL2377742 | 0.76 | RAD52 (0.62) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL19409829 | 0.76 | RAD52 (0.62) | MAPTSMN1; SMN2CDK9CCNKCCNA2 | |
| SCHEMBL17466591 | 0.74 | CDK9 (0.59) | MAPTSMN1; SMN2CDK9CCNKCCNA2 | |
| SCHEMBL11788144 | 0.73 | LMNA (0.74) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL16069915 | 0.73 | CDK9 (0.55) | MAPTSMN1; SMN2CDK9CCNKCCNA2 | |
| SCHEMBL4417817 | 0.73 | MAPT (0.67) | MAPTMEN1MAPK1KMT2ATDP1 | |
| SCHEMBL20816284 | 0.71 | GAA (0.52) | MAPTSMN1; SMN2KDM1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624897-B2 | Chlorobenzene substituted azaaryl compounds | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-04-21 | — | — | US | disclosed |
| US-10624897-B2 | Chlorobenzene substituted azaaryl compounds | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-04-21 | — | — | US | disclosed |
| US-20190083499-A1 | CHLOROBENZENE SUBSTITUTED AZAARYL COMPOUNDS | TAIPEI MEDICAL UNIVERSITY (TW) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624897-B2 | Chlorobenzene substituted azaaryl compounds | MKI67, CTCF, CDKN1A | MAPT 4439/4885MEN1 3618/4885MAPK1 4003/4885 |
| US-20190083499-A1 | CHLOROBENZENE SUBSTITUTED AZAARYL COMPOUNDS | MKI67, CTCF, CDKN1A | MAPT 4439/4885MEN1 3618/4885MAPK1 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.