Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 6/20 | 0.42 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837480 | 0.84 | NPC1 (0.45) | LPAR1LPAR5LTA4HMAPTRAB9A | |
| SCHEMBL20837581 | 0.83 | HDAC3 (0.42) | LTA4HMAPTBCHEACHEALDH1A1 | |
| SCHEMBL20837477 | 0.82 | MAPT (0.37) | LTA4HMAPTRAB9ABCHEACHE | |
| SCHEMBL16663712 | 0.79 | ADRB3 (0.39) | LPAR1LPAR5LTA4HCETP | |
| SCHEMBL20837540 | 0.78 | MEP1B (0.40) | LTA4HMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL18070848 | 0.78 | FFAR1 (0.38) | LPAR1LPAR5LTA4HCETPMAPT | |
| SCHEMBL2997165 | 0.77 | CYP4F2 (0.46) | LPAR1LPAR5MAPTBCHEACHE | |
| SCHEMBL20837712 | 0.76 | CYP3A4 (0.40) | LPAR1LPAR5LTA4HMAPTRAB9A | |
| SCHEMBL13206909 | 0.76 | MEP1B (0.43) | MAPTRAB9ABCHEACHEKMT2A | |
| SCHEMBL2992339 | 0.76 | PDE6D (0.43) | LPAR1LPAR5MAPTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3059224-B1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | TOA EIYO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |