Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837481 | 0.82 | LPAR1 (0.43) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL16663715 | 0.82 | MMEL1 (0.36) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL18030877 | 0.81 | FFAR1 (0.34) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL20837537 | 0.81 | RXRA (0.41) | MEP1BALOX5 | |
| SCHEMBL13206909 | 0.81 | MEP1B (0.43) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL20837540 | 0.80 | MEP1B (0.40) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL3768331 | 0.80 | OPRK1 (0.47) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL20837545 | 0.80 | PLA2G4B (0.42) | LTA4HMEP1BBCHEACHE | |
| SCHEMBL20837560 | 0.79 | PDE6D (0.32) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL20837581 | 0.78 | HDAC3 (0.42) | MAPTALDH1A1KDM4ELTA4HL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3059224-B1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | TOA EIYO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |