Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839484 | 0.77 | ABCG2 (0.68) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20839620 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11654042 | 0.77 | MEN1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL5666338 | 0.77 | KMT2A (0.78) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11427459 | 0.76 | KMT2A (0.61) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20839497 | 0.75 | RXFP1 (0.59) | KMT2AMEN1RAB9A | |
| SCHEMBL5665828 | 0.75 | KMT2A (0.74) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14018735 | 0.74 | ABCG2 (0.89) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8711203 | 0.74 | RAB9A (0.74) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5668739 | 0.74 | KMT2A (0.65) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057969-A1 | DUAL AGONISTS OF FXR AND PPARδ AND THEIR USES | Johann Wolfgang Goethe-Universität (DE) | 2019-03-28 | — | — | WO | disclosed |