SCHEMBL20840708

SCHEMBL20840708

Nc1ccc2c(-c3cc4cccc5ccc6ccc(N)c3c6c54)c3ccccc3cc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.47
CYP1A2 P05177 1/20 0.47
FYN P06241 1/20 0.47
MAOA P21397 1/20 0.47
ACHE P22303 1/20 0.47
AHR P35869 1/20 0.47
ALDH1A1 P00352 7/20 0.41
HSD17B10 Q99714 6/20 0.41
CYP3A4 P08684 3/20 0.41
CASP1 P29466 3/20 0.41
HIF1A Q16665 2/20 0.41
ALOX15 P16050 2/20 0.41
CASP7 P55210 2/20 0.41
HBB P68871 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PLAU P00749 1/20 0.40
CES1 P23141 1/20 0.39
HPRT1 P00492 1/20 0.37
NQO2 P16083 2/20 0.37
CTDSP1 Q9GZU7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651697 0.79 ALDH1A1 (0.49) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL28155411 0.75 CDK4 (0.38) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL20407332 0.74 ALDH1A1 (0.58) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL14742580 0.72 PLAU (0.55) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL1527441 0.72 ALDH1A1 (0.65) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL28682862 0.71 CYP1A2 (0.66) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL25785683 0.71 ALDH1A1 (0.44) CYP1A2ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL2325454 0.70 ALDH1A1 (0.53) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL6426697 0.70 HPRT1 (0.64) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL6138724 0.70 HPRT1 (0.64) ERBB2CYP1A2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10240084-B2 Non-crystallizable pi-conjugated molecular glass mixtures, charge transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof for organic light emitting diodes and other organic electronics and photonics applications MOLECULAR GLASSES, INC. (US) 2019-03-26 US disclosed