SCHEMBL4651697

SCHEMBL4651697

Nc1ccc2c(-c3cccc4ccc5cc6ccccc6cc5c34)c3ccccc3cc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.49
HSD17B10 Q99714 7/20 0.49
HIF1A Q16665 4/20 0.49
CASP1 P29466 3/20 0.49
CYP3A4 P08684 2/20 0.49
CASP7 P55210 2/20 0.49
ALOX15 P16050 1/20 0.49
HBB P68871 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CYP1A2 P05177 2/20 0.44
ERBB2 P04626 1/20 0.44
FYN P06241 1/20 0.44
MAOA P21397 1/20 0.44
ACHE P22303 1/20 0.44
AHR P35869 1/20 0.44
PLAU P00749 1/20 0.42
CES1 P23141 1/20 0.42
SOS1 Q07889 1/20 0.40
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL364084 0.88 CES1 (0.49) ALDH1A1HSD17B10HIF1ACASP1CASP7
SCHEMBL27587539 0.86 CES1 (0.47) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL23928805 0.82 CYP1A2 (0.48) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL2325454 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL20840708 0.79 ERBB2 (0.47) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL4867555 0.78 CES1 (0.42) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL25785683 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL11701192 0.77 ALDH1A1 (0.60) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL28774117 0.76 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACASP1CYP3A4
SCHEMBL2551156 0.76 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966344-A2 AMINO ANTHRACENE COMPOUNDS IN OLED DEVICES Eastman Kodak Company (US) 2008-09-10 EP disclosed
WO-2007075286-A2 AMINO ANTHRACENE COMPOUNDS IN OLED DEVICES EASTMAN KODAK COMPANY (US) 2007-07-05 WO disclosed