SCHEMBL20840786

SCHEMBL20840786

CCPCC(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20840769 0.86 TSHR (0.42) USP2MAPTTSHRGAACYP1A2
SCHEMBL20840780 0.85
SCHEMBL11904906 0.79 TSHR (0.40) USP2MAPTTSHRGAACYP1A2
SCHEMBL12938888 0.77 TSHR (0.36) USP2MAPTTSHRGAACYP1A2
SCHEMBL13475913 0.77 TSHR (0.36) USP2MAPTTSHRGAACYP1A2
SCHEMBL10064498 0.76 USP2 (0.36) USP2MAPTTSHRGAA
SCHEMBL18412470 0.75 TSHR (0.35) USP2MAPTTSHRGAA
SCHEMBL14673666 0.74 THRB (0.39) USP2MAPTTSHRGAACYP1A2
SCHEMBL9317736 0.74 THRB (0.39) USP2MAPTTSHRGAACYP1A2
SCHEMBL9317944 0.74 THRB (0.39) USP2MAPTTSHRGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10241251-B2 Polarizing plate and image display device FUJIFILM CORPORATION (JP) 2019-03-26 US disclosed