SCHEMBL9317944

SCHEMBL9317944

C=C(C)C(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
TSHR P16473 5/20 0.38
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
GAA P10253 1/20 0.34
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
RECQL P46063 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317736 1.00 THRB (0.39) THRBTSHRUSP2MAPTGAA
SCHEMBL14673664 1.00 THRB (0.39) THRBTSHRUSP2MAPTGAA
SCHEMBL14673666 1.00 THRB (0.39) THRBTSHRUSP2MAPTGAA
SCHEMBL25699902 0.98 THRB (0.40) THRBTSHRUSP2MAPTGAA
SCHEMBL14674585 0.94 THRB (0.41) THRBTSHRUSP2MAPTGAA
SCHEMBL30360194 0.89 THRB (0.47) THRBTSHRALDH1A1TDP1POLB
SCHEMBL3843423 0.87 THRB (0.48) THRBTSHRALDH1A1TDP1POLB
SCHEMBL2031372 0.85 TSHR (0.44) THRBTSHRUSP2MAPTGAA
SCHEMBL285648 0.85 TSHR (0.44) THRBTSHRUSP2MAPTGAA
SCHEMBL712581 0.85 TSHR (0.44) THRBTSHRUSP2MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4737556-A CROSSLINKED COPOLYMERS OF FLUOROALKYL ACRYLIC ESTERS; UNNECESSARY TO STERILIZE BY BOILING; ANTISOILANTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-04-12 US claimed
US-10752833-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
US-20190194535-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2019-06-27 US disclosed
US-10119070-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-11-06 US disclosed
US-9885883-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-02-06 US disclosed
US-20170088771-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2017-03-30 US disclosed
EP-2951620-B1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORP (JP) 2017-03-01 EP disclosed
US-9574067-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2017-02-21 US disclosed
EP-2739997-B1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORP (JP) 2016-06-08 EP disclosed
US-20160085090-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2016-03-24 US disclosed
US-20130056682-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-03-07 US disclosed
US-20130057824-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-03-07 US disclosed
US-20130033776-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-02-07 US disclosed
US-20130032758-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-02-07 US disclosed
EP-0294976-B1 Non-hydrous soft contact lens and process for producing the same JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-01-05 EP disclosed
EP-0228193-B1 NON-HYDROUS SOFT CONTACT LENS AND PROCESS FOR PRODUCING THE SAME JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-10-31 EP disclosed
US-4882403-A Non-hydrous soft contact lens and process for producing the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-11-21 US disclosed
EP-0294976-A2 Non-hydrous soft contact lens and process for producing the same CIBA-GEIGY AG (CH) 1988-12-14 EP disclosed
US-4737556-A CROSSLINKED COPOLYMERS OF FLUOROALKYL ACRYLIC ESTERS; UNNECESSARY TO STERILIZE BY BOILING; ANTISOILANTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-04-12 US disclosed
EP-0228193-A1 Non-hydrous soft contact lens and process for producing the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-08 EP disclosed