SCHEMBL2084086

SCHEMBL2084086

FC(F)(F)OC1=CC=CC[CH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL913118 0.82
SCHEMBL6017143 0.78
SCHEMBL18301588 0.74 ALDH1A1 (0.33)
SCHEMBL1804487 0.72
SCHEMBL752148 0.70
SCHEMBL8441081 0.70
SCHEMBL18944438 0.68
SCHEMBL784939 0.65
SCHEMBL4639726 0.65
SCHEMBL3272739 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140135216-A1 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-05-15 US disclosed
US-7863302-B2 Compounds and methods for modulating FX-receptors ELI LILLY AND COMPANY (US) 2011-01-04 US disclosed
WO-2010081904-A1 4 ( 1H) -PYRIDINONE DERIVATIVES AND THEIR USE AS ANTIMALARIA AGENTS GLAXO GROUP LIMITED (GB) 2010-07-22 WO disclosed
US-20080306125-A1 Compounds and Methods for Modulating Fx-Receptors JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT 2008-12-11 US disclosed
US-20080064690-A1 PYRAZOLE-AMIDES AND -SULFONAMIDES ICAGEN, INC. (US) 2008-03-13 US disclosed
US-7223782-B2 Pyrazole-amides and -sulfonamides ICAGEN, INC. (US) 2007-05-29 US disclosed
US-20050049237-A1 Pyrazole-amides and -sulfonamides ICAGEN, INC. (US) 2005-03-03 US disclosed
US-5886176-A Process for preparing sulphonylurea salts BAYER AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
WO-1996022284-A1 METHOD OF PREPARING SULFONYL UREAS BAYER AKTIENGESELLSCHAFT (DE) 1996-07-25 WO disclosed
EP-0559044-A1 Process for the preparation of sulfonylurea salts BAYER AG (DE) 1993-09-08 EP disclosed
US-5151514-A Triazine substituted herbicides BAYER AKTIENGESELLSCHAFT (DE) 1992-09-29 US disclosed
US-5142060-A Herbicidal substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-5089627-A Chemical intermediates therefor BAYER AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-5085687-A HERBICIDAL SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0416319-A2 Process for the preparation of sulfonylisoureas BAYER AG (DE) 1991-03-13 EP disclosed
US-4988381-A HERBICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed