Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003584 | 0.90 | CA2 (0.50) | CA2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL850537 | 0.86 | CA2 (0.47) | CA2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL7777862 | 0.86 | CA2 (0.47) | CA2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL849829 | 0.86 | CA2 (0.47) | CA2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL24123350 | 0.86 | CA1 (0.45) | CA2CA1MAPK1CA12CA9 | |
| SCHEMBL2058940 | 0.86 | CA2 (0.55) | CA2SLC1A2SLC1A1CA1MAPK1 | |
| SCHEMBL11198154 | 0.85 | CA2 (0.48) | CA2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL1629287 | 0.85 | CA2 (0.50) | CA2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL17012419 | 0.85 | TDP1 (0.48) | CA2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL25914044 | 0.83 | S1PR2 (0.46) | CA2GRIK1GRIK2CA1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239862-B2 | Benzazepine compounds, conjugates, and uses thereof | SILVERBACK THERAPEUTICS, INC. (US) | 2019-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239862-B2 | Benzazepine compounds, conjugates, and uses thereof | TLR8, TLR3, TLR5 | CA2 3618/4885GRIK1 165/4885GRIK2 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.