Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.43 |
| ▸ | KDM5A | P29375 | 5/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25414195 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5CA2 | |
| SCHEMBL25317185 | 0.86 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5CA2 | |
| SCHEMBL13003584 | 0.85 | CA2 (0.50) | CA2GRIK1GRIK2GPR84CA12 | |
| SCHEMBL20840951 | 0.83 | CA2 (0.47) | CA2GRIK1GRIK2GPR84CA12 | |
| SCHEMBL25320247 | 0.83 | MAPT (0.51) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL850537 | 0.82 | CA2 (0.47) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL7777862 | 0.82 | CA2 (0.47) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL849829 | 0.82 | CA2 (0.47) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL6948533 | 0.82 | GRIK1 (0.54) | S1PR2S1PR1S1PR3S1PR5CA2 | |
| SCHEMBL6950336 | 0.82 | GRIK1 (0.54) | S1PR2S1PR1S1PR3S1PR5CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114943-A2 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2023-06-22 | — | — | WO | disclosed |