Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.46 |
| ▸ | PNMT | P11086 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735079 | 0.83 | TAAR1 (0.67) | PNMTTAAR1 | |
| Hydrochloric Acid SCHEMBL8975991 | 0.80 | CSNK2A1 (0.52) | CSNK2A1PNMTTAAR1LOXL2LOX | |
| SCHEMBL28879957 | 0.78 | LOXL2 (0.46) | CSNK2A1PNMTTAAR1LOXL2LOX | |
| SCHEMBL29875484 | 0.78 | LOXL2 (0.46) | CSNK2A1PNMTTAAR1LOXL2LOX | |
| SCHEMBL29349576 | 0.78 | PNMT (0.67) | CSNK2A1PNMTTAAR1LOXL2CSNK2A2 | |
| SCHEMBL112200 | 0.78 | PNMT (0.67) | CSNK2A1PNMTTAAR1LOXL2CSNK2A2 | |
| SCHEMBL2956766 | 0.77 | S1PR1 (0.41) | PNMTTAAR1CYP2A6IDO1 | |
| SCHEMBL5430585 | 0.77 | RECQL (0.42) | PNMTTAAR1IDO1 | |
| SCHEMBL5158103 | 0.77 | CYP4F2 (0.42) | PNMTTAAR1IDO1 | |
| SCHEMBL5085475 | 0.77 | IDO1 (0.37) | PNMTTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609868-B1 | TETRAHYDROQUINOLINE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2023-10-18 | — | — | EP | disclosed |
| WO-2019057946-A1 | MULTI-CYCLIC AROMATIC COMPOUNDS AS FACTOR D INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-03-28 | — | — | WO | disclosed |