SCHEMBL20845091

SCHEMBL20845091

C1=C\c2ccc(-c3nc(-c4ccccc4)cc(-c4cnc(-c5ccccc5)nc4)n3)cc2-c2ccc3ccccc3c2Sc2ccccc2-c2ccccc2/1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ NTSR1 P30989 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MAOB P27338 2/20 0.32
▸ MAOA P21397 1/20 0.32
▸ NFKB1 P19838 1/20 0.30
▸ NFKB2 Q00653 1/20 0.30
▸ RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20845248 0.97 MAPT (0.33) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL20845092 0.93 HPGD (0.34) MAPTSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL20845250 0.92 ALDH1A1 (0.36) MAPTSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL20222819 0.90 MAPT (0.36) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL20845056 0.89 MAPT (0.34) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL20845242 0.88 SMN1; SMN2 (0.34) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL20845241 0.88 MEN1 (0.39) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL20845087 0.88 DHODH (0.37) MAPTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL20845088 0.88 DHODH (0.34) MAPTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL20222678 0.87 MAPT (0.37) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190092745-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092745-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME SCO2, AOX1, ORC3 MAPT 4294/4885NPC1 4683/4885RAB9A 635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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