Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212465 | 0.77 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL2083841 | 0.75 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL2087481 | 0.75 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL3809137 | 0.74 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL2085742 | 0.74 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL3210842 | 0.71 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3724191 | 0.68 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL3870648 | 0.63 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3214345 | 0.63 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL2086149 | 0.63 | CRHR1 (0.42) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163935-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-04-24 | — | — | US | disclosed |