Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607855 | 0.91 | THRB (0.47) | THRBPDE6DCYP2C19TUBB4ATUBB | |
| SCHEMBL17952393 | 0.90 | THRB (0.45) | THRBPDE6DCYP2C19LMNACYP1A2 | |
| SCHEMBL20342948 | 0.87 | THRB (0.45) | THRBPDE6DBACE1SMN1; SMN2LMNA | |
| SCHEMBL18432923 | 0.87 | BACE1 (0.45) | THRBCYP2C19TUBB4ATUBBTUBA3C | |
| SCHEMBL20925168 | 0.85 | PDE6D (0.46) | THRBPDE6DTUBB4ATUBBTUBA3C | |
| SCHEMBL9607786 | 0.84 | THRB (0.42) | THRBPDE6DCYP2C19TUBB4ATUBB | |
| SCHEMBL19311598 | 0.84 | THRB (0.42) | THRBPDE6DCYP2C19TUBB4ATUBB | |
| SCHEMBL20643578 | 0.83 | THRB (0.42) | THRBPDE6DCYP2C19APPKDM4E | |
| SCHEMBL22600469 | 0.83 | ELANE (0.44) | THRBPDE6DCYP2C19TUBB4ATUBB | |
| SCHEMBL20342991 | 0.83 | THRB (0.49) | THRBPDE6DSMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2725083-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-03-27 | — | — | EP | disclosed |