SCHEMBL9607855

SCHEMBL9607855

C=CC(=O)Oc1ccc(-c2ccc(-c3ccc(OC(=O)C=C)cc3)c(F)c2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.47
PDE6D O43924 1/20 0.41
KIF11 P52732 1/20 0.34
CYP2C19 P33261 2/20 0.33
BACE1 P56817 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33
TUBB8 Q3ZCM7 1/20 0.33
TUBA3E Q6PEY2 1/20 0.33
TUBA1A Q71U36 1/20 0.33
TUBA1C Q9BQE3 1/20 0.33
TUBB6 Q9BUF5 1/20 0.33
TUBB2B Q9BVA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20925168 0.94 PDE6D (0.46) THRBPDE6DBACE1SMN1; SMN2TUBB4A
SCHEMBL9607786 0.92 THRB (0.42) THRBPDE6DKIF11CYP2C19BACE1
SCHEMBL20342948 0.92 THRB (0.45) THRBPDE6DBACE1SMN1; SMN2LMNA
SCHEMBL18432923 0.92 BACE1 (0.45) THRBCYP2C19BACE1SMN1; SMN2TUBB4A
SCHEMBL17952393 0.92 THRB (0.45) THRBPDE6DCYP2C19LMNACYP1A2
SCHEMBL19311598 0.92 THRB (0.42) THRBPDE6DKIF11CYP2C19TUBB4A
SCHEMBL20847309 0.91 THRB (0.44) THRBPDE6DCYP2C19BACE1SMN1; SMN2
SCHEMBL18511687 0.91 THRB (0.41) THRBPDE6D
SCHEMBL21592059 0.91 THRB (0.41) THRBPDE6DCYP2C19BACE1KDM4E
SCHEMBL20664399 0.89 THRB (0.40) THRBPDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024132893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-2607451-A1 Liquid crystalline medium Merck Patent GmbH (DE) 2013-06-26 EP disclosed
US-20130037745-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-02-14 US disclosed
US-20130037745-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-02-14 US disclosed
WO-2012130380-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-10-04 WO disclosed
WO-2012126562-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-09-27 WO disclosed
WO-2012097858-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2012-07-26 WO disclosed
WO-2012079710-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-06-21 WO disclosed
WO-2012072201-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-06-07 WO disclosed
WO-2012069151-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-05-31 WO disclosed
EP-2457975-A2 Liquid-crystalline mixtures Merck Patent GmbH (DE) 2012-05-30 EP disclosed