Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 4/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | BECN1 | Q14457 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231333 | 0.82 | CYP17A1 (0.59) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL29096680 | 0.82 | CYP17A1 (0.59) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL3790541 | 0.81 | CYP17A1 (0.50) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL15139200 | 0.80 | CYP17A1 (0.52) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL18570243 | 0.79 | CYP17A1 (0.61) | CYP17A1PSMB8MAP4K4NAMPTBCL2 | |
| SCHEMBL20865536 | 0.79 | CYP17A1 (0.68) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL7094083 | 0.78 | LMNA (0.52) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL6165687 | 0.78 | BRD4 (0.48) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL6164154 | 0.78 | BRD4 (0.48) | CYP17A1PSMB8BRD4CREBBPMAP4K4 | |
| SCHEMBL6164774 | 0.78 | TTK (0.55) | CYP17A1PSMB8BRD4CREBBPMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2020-09-03 | — | — | US | disclosed |
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | MKI67, PKD1, ETV6 | CYP17A1 1299/4885PSMB8 2899/4885BRD4 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.