Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.68 |
| ▸ | RARA | P10276 | 2/20 | 0.68 |
| ▸ | RARG | P13631 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736771 | 0.87 | RARB (0.78) | RARBRARARARGMCL1ALDH1A1 | |
| SCHEMBL669282 | 0.85 | RARB (0.54) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL30641680 | 0.85 | RARB (0.60) | RARBRARARARGMCL1RXRA | |
| SCHEMBL16534058 | 0.85 | RARB (0.60) | RARBRARARARGMCL1RXRA | |
| SCHEMBL20556331 | 0.83 | RARB (0.68) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL15717036 | 0.83 | RXRA (0.53) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL10052771 | 0.82 | MCL1 (0.61) | RARBRARARARGSMN1; SMN2MCL1 | |
| SCHEMBL31725051 | 0.82 | ACMSD (0.63) | RARBRARARARGMCL1KDM4E | |
| SCHEMBL4652842 | 0.82 | RARB (0.58) | RARBRARARARGMCL1ALDH1A1 | |
| SCHEMBL121429 | 0.82 | ACMSD (0.63) | RARBRARARARGMCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |