Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804834 | 0.82 | DRD4 (0.56) | DRD4SIGMAR1LMNANPC1RAB9A | |
| SCHEMBL22388848 | 0.82 | DRD4 (0.56) | DRD4CHRM4SIGMAR1LMNAPOLB | |
| SCHEMBL9942641 | 0.81 | NPC1 (0.63) | DRD4SIGMAR1LMNAPOLBNPC1 | |
| SCHEMBL6889419 | 0.80 | GAA (0.54) | NPC1RAB9AKDM4EMAPTTP53 | |
| SCHEMBL12385909 | 0.80 | DRD4 (0.77) | DRD4SIGMAR1LMNAPOLBDRD2 | |
| SCHEMBL8312103 | 0.79 | DRD4 (0.70) | DRD4POLBDRD2DRD3KDM4E | |
| SCHEMBL7399044 | 0.79 | DRD4 (0.65) | DRD4SIGMAR1LMNAPOLBNCF1 | |
| SCHEMBL3448210 | 0.78 | DRD4 (0.59) | DRD4SIGMAR1LMNAPOLBNCF1 | |
| SCHEMBL6031812 | 0.77 | DRD4 (1.00) | DRD4SIGMAR1DRD2DRD3KDM4E | |
| SCHEMBL5548733 | 0.76 | DRD4 (0.77) | DRD4SIGMAR1DRD2DRD3MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |