Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.65 |
| ▸ | NCF1 | P14598 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP5 | P51878 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448210 | 0.84 | DRD4 (0.59) | DRD4NCF1TSHRHTTPOLB | |
| SCHEMBL13173988 | 0.81 | MAPT (0.61) | DRD4TSHRHTTPOLBDRD2 | |
| SCHEMBL6031812 | 0.79 | DRD4 (1.00) | DRD4HTTSIGMAR1DRD2DRD3 | |
| SCHEMBL20847693 | 0.79 | DRD4 (0.61) | DRD4NCF1POLBSIGMAR1DRD2 | |
| SCHEMBL12385909 | 0.79 | DRD4 (0.77) | DRD4POLBSIGMAR1DRD2DRD3 | |
| SCHEMBL11531669 | 0.78 | DRD4 (0.69) | DRD4HTTSIGMAR1DRD2DRD3 | |
| SCHEMBL12192096 | 0.77 | DRD4 (0.51) | DRD4NCF1POLBDRD2DRD3 | |
| SCHEMBL8092355 | 0.77 | DRD4 (0.65) | DRD4POLBSIGMAR1DRD2DRD3 | |
| SCHEMBL23860777 | 0.77 | DRD4 (0.58) | DRD4SIGMAR1DRD2DRD3LMNA | |
| SCHEMBL28751367 | 0.77 | DRD4 (0.58) | DRD4TSHRPOLBSIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |