Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798019 | 0.83 | CHRNB2 (0.42) | DRD4SIGMAR1TRPV6CHRNB2CHRNA4 | |
| SCHEMBL20847693 | 0.82 | DRD4 (0.61) | DRD4SIGMAR1KDM4EALDH1A1LMNA | |
| SCHEMBL6888786 | 0.81 | CHRNB2 (0.57) | CHRNB2CHRNA4KDM4EMAPTGFER | |
| SCHEMBL11923385 | 0.79 | SIGMAR1 (0.79) | DRD4SIGMAR1MAPK1ALDH1A1LMNA | |
| SCHEMBL22388848 | 0.78 | DRD4 (0.56) | DRD4SIGMAR1LMNANPC1RAB9A | |
| SCHEMBL4160649 | 0.77 | TRPV6 (0.60) | SIGMAR1TRPV6 | |
| Hydrochloric Acid SCHEMBL11213408 | 0.77 | SIGMAR1 (0.77) | DRD4SIGMAR1MAPK1ALDH1A1LMNA | |
| Bromide SCHEMBL4169169 | 0.76 | TRPV6 (0.58) | SIGMAR1TRPV6 | |
| SCHEMBL6884588 | 0.76 | CHRNB2 (0.61) | CHRNB2CHRNA4KDM4EALDH1A1HTR3A | |
| SCHEMBL6660468 | 0.76 | CASP1 (0.62) | DRD4SIGMAR1MAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169202-A1 | VASOPRESSIN RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | Neumora Therapeutics, Inc. | 2019-06-06 | — | — | US | disclosed |
| WO-2019050988-A1 | VASOPRESSIN RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | BLACKTHORN THERAPEUTICS, INC. (US) | 2019-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169202-A1 | VASOPRESSIN RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | AVPR1A, AVPR2, AVPR1B | DRD4 406/4885SIGMAR1 238/4885TRPV6 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.