Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22542015 | 0.85 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL22542136 | 0.84 | HTR2C (0.49) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL31223147 | 0.82 | HTR2C (0.42) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL28134205 | 0.82 | SLC6A2 (0.43) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL28128243 | 0.82 | HTR2C (0.42) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL22542124 | 0.81 | HTR2C (0.46) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL22542150 | 0.81 | MEN1 (0.44) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL22542151 | 0.81 | SLC6A2 (0.43) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL22542138 | 0.80 | SETDB1 (0.46) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL22542126 | 0.80 | HTR6 (0.43) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164395-B1 | INDANE AND INDOLINE DERIVATIVES AND THE USE THEREOF AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS | NOVARTIS AG (CH) | 2019-03-27 | — | — | EP | disclosed |