Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23334744 | 0.88 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| Tert-Butyl Formate SCHEMBL28839897 | 0.88 | HTR6 (0.38) | HTR2CSLC6A2SLC6A4SLC6A3GABRA1 | |
| SCHEMBL27568437 | 0.83 | SLC6A2 (0.38) | HTR2CSLC6A2SLC6A4SLC6A3CHRNB2 | |
| SCHEMBL20847703 | 0.82 | HTR2C (0.51) | HTR2CSLC6A2SLC6A4SLC6A3GABRA1 | |
| SCHEMBL30226317 | 0.81 | SLC6A2 (0.41) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL19012966 | 0.81 | SLC6A2 (0.41) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL31223147 | 0.81 | HTR2C (0.42) | HTR2CSLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL28134205 | 0.81 | SLC6A2 (0.43) | HTR2CSLC6A2SLC6A4SLC6A3CHRNB2 | |
| SCHEMBL26040667 | 0.79 | HTR1D (0.52) | HTR6PLG | |
| SCHEMBL19022096 | 0.78 | HTR6 (0.48) | HTR2CSLC6A2SLC6A4SLC6A3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470985-A | Indane and indoline derivatives as soluble guanylate cyclase activators and uses thereof | 诺华股份有限公司 | 2017-03-01 | — | — | CN | disclosed |