Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679135 | 1.00 | MEN1 (0.36) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL29017754 | 1.00 | MEN1 (0.36) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL1934562 | 1.00 | MEN1 (0.36) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL6679121 | 1.00 | MEN1 (0.36) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL12616436 | 1.00 | MEN1 (0.36) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| Hydrochloric Acid SCHEMBL16667769 | 0.98 | MEN1 (0.35) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL6673873 | 0.83 | ALDH1A1 (0.35) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL6673263 | 0.83 | ALDH1A1 (0.35) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL6673877 | 0.83 | ALDH1A1 (0.35) | MEN1KMT2ATSHRMAPK1SLC1A2 | |
| SCHEMBL17474576 | 0.82 | SLC6A1 (0.42) | TSHRLMNAGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057103-A1 | JAK INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION IN THE FIELD OF MEDICINE | 上海华汇拓医药科技有限公司 | 2019-03-28 | — | — | WO | disclosed |