Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083500 | 0.85 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL2085857 | 0.80 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL12936318 | 0.78 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DSCN10A | |
| SCHEMBL2085975 | 0.76 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DSCN10A | |
| SCHEMBL2082824 | 0.70 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL2084625 | 0.70 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL2083722 | 0.70 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL2084336 | 0.70 | PDE4A (0.88) | PDE4APDE4BPDE4CPDE4DMAOA | |
| Hydrochloric Acid SCHEMBL2084966 | 0.69 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL2082733 | 0.69 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863446-B2 | Heterocycles | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-01-04 | — | — | US | disclosed |
| US-20080207606-A1 | Novel heterocycles | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207606-A1 | Novel heterocycles | GPR4, UACA, PDE4A | PDE4A 3/4885PDE4B 8/4885PDE4C 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.