SCHEMBL20848856

SCHEMBL20848856

Cc1ccc(-c2ccc3c(c2)c2cc(-c4ccc(C)cc4C)ccc2n3-c2ccc(C#N)cc2-c2ccc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2-n2c3ccc(-c4ccc(C)cc4C)cc3c3cc(-c4ccc(C)cc4C)ccc32)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.32
RXRG P48443 1/20 0.32
ELANE P08246 2/20 0.32
KIF11 P52732 1/20 0.32
RXRB P28702 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
AR P10275 2/20 0.30
TACR1 P25103 1/20 0.30
ICMT O60725 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20849593 0.96 RXRA (0.32) RXRARXRGELANEKIF11RXRB
SCHEMBL20849198 0.96 RXRA (0.33) RXRARXRGELANEKIF11RXRB
SCHEMBL20849219 0.96 RXRA (0.33) RXRARXRGELANEKIF11RXRB
SCHEMBL20849227 0.96 PTGER4 (0.33) RXRARXRGELANEARTACR1
SCHEMBL20849280 0.93 RXRA (0.35) RXRARXRGELANEKIF11RXRB
SCHEMBL20849534 0.92 AR (0.37) RXRARXRGKIF11RXRBPTGDR2
SCHEMBL20848552 0.92 PTGER4 (0.33) RXRARXRGELANEARTACR1
SCHEMBL20848877 0.92 PTGER4 (0.33) RXRARXRGELANEKIF11AR
SCHEMBL20848851 0.91 RXRA (0.33) RXRARXRGELANEKIF11RXRB
SCHEMBL21399464 0.91 KIF11 (0.36) ELANEKIF11PTGDR2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978646-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-13 US disclosed
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10978646-B2 Organic molecules for use in optoelectronic devices OCIAD2, OCIAD1, POU2F1 RXRA 1822/4885RXRG 1841/4885ELANE 4164/4885
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 RXRA 1822/4885RXRG 1841/4885ELANE 4164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.