SCHEMBL20848934

SCHEMBL20848934

N#Cc1cccc(-n2c3ccccc3c3cc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)ccc32)c1-c1c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cccc1-n1c2ccccc2c2cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)ccc21

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.33
ICMT O60725 3/20 0.32
TACR1 P25103 2/20 0.32
PDK2 Q15119 1/20 0.32
PTPN5 P54829 1/20 0.32
PGR P06401 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
GABRA1 P14867 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GPBAR1 Q8TDU6 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848579 0.96 TACR1 (0.35) ARICMTTACR1PDK2GRIN1
SCHEMBL20849616 0.95 GABRA1 (0.36) ARPTPN5PGRGABRA1GABRG2
SCHEMBL20849092 0.94 AR (0.35) ARICMTTACR1PGRGPBAR1
SCHEMBL20848572 0.94 KIF11 (0.36) ARTACR1PDK2PTPN5GABRA1
SCHEMBL20848932 0.93 AR (0.38) ARICMTTACR1PTPN5PGR
SCHEMBL20849018 0.93 KIF11 (0.35) ARTACR1PDK2PTPN5GRIN1
SCHEMBL20848581 0.93 AR (0.34) ARICMTTACR1PDK2GRIN1
SCHEMBL20849254 0.93 AR (0.42) ARICMTTACR1PDK2PTPN5
SCHEMBL20849342 0.92 AR (0.38) ARICMTTACR1PGR
SCHEMBL20849333 0.92 GABRA1 (0.38) ARPDK2PTPN5PGRGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978646-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-13 US disclosed
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10978646-B2 Organic molecules for use in optoelectronic devices OCIAD2, OCIAD1, POU2F1 AR 3706/4885ICMT 616/4885TACR1 2846/4885
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 AR 3706/4885ICMT 616/4885TACR1 2846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.