Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20305870 | 0.83 | POLB (0.52) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL22258209 | 0.81 | TDP1 (0.52) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL24107225 | 0.81 | L3MBTL1 (0.51) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL24414096 | 0.80 | TDP1 (0.51) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL12094229 | 0.79 | POLB (0.58) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL24934415 | 0.78 | TDP1 (0.45) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL14872363 | 0.76 | MRGPRX4 (0.57) | ALDH1A1MAPK1RAB9ANPSR1ATM | |
| SCHEMBL24773946 | 0.76 | TDP1 (0.44) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL24499911 | 0.74 | BRD4 (0.55) | KMT2ALMNAALDH1A1POLBMAPT | |
| SCHEMBL29329017 | 0.74 | ALDH1A1 (0.54) | KMT2ATDP1LMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815217-B2 | Inhibitor of p38 MAP kinase | RESPIVERT LTD. (GB) | 2020-10-27 | — | — | US | disclosed |
| US-20190092752-A1 | INHIBITOR OF p38 MAP KINASE | TOPIVERT PHARMA LTD. (GB) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815217-B2 | Inhibitor of p38 MAP kinase | MAPK1, MAPKAPK2, MAP3K1 | KMT2A 3285/4885TDP1 1379/4885LMNA 1566/4885 |
| US-20190092752-A1 | INHIBITOR OF p38 MAP KINASE | MAPK1, MAPKAPK2, MAP3K1 | KMT2A 3285/4885TDP1 1379/4885LMNA 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.