Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15712242 | 0.91 | LMNA (0.52) | P2RX3LMNAALDH1A1MAPTCA12 | |
| SCHEMBL15712251 | 0.85 | P2RX3 (0.47) | P2RX3LMNAALDH1A1MAPTCA12 | |
| SCHEMBL15712243 | 0.82 | P2RX3 (0.49) | P2RX3LMNAALDH1A1MAPTCA9 | |
| SCHEMBL8358799 | 0.80 | NR4A2 (0.53) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL15712210 | 0.79 | ERBB2 (0.48) | P2RX3LMNAMAPTP2RX7SMN1; SMN2 | |
| SCHEMBL15712464 | 0.77 | NR1I2 (0.56) | — | |
| SCHEMBL15712217 | 0.77 | POLB (0.43) | P2RX3LMNAMAPTP2RX7SMN1; SMN2 | |
| SCHEMBL15712354 | 0.76 | MAPT (0.49) | P2RX3LMNAALDH1A1MAPTP2RX7 | |
| SCHEMBL15712637 | 0.75 | ERBB2 (0.50) | P2RX3LMNAP2RX7SMN1; SMN2 | |
| SCHEMBL15712713 | 0.75 | HDAC1 (0.47) | P2RX3LMNAALDH1A1MAPTCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915804-B1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF AS TNF ALPHA INHIBITORS | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-03-27 | — | — | EP | disclosed |